Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.47 |
| ▸ | IGF1R | P08069 | 3/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118532 | 0.85 | DAO (0.61) | DAOALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL194512 | 0.78 | DAO (0.69) | DAOALDH1A1KDM4EHPGDNQO2 | |
| SCHEMBL5710156 | 0.76 | L3MBTL1 (0.45) | ALDH1A1KDM4EHSD17B10NTRK1IGF1R | |
| SCHEMBL28905782 | 0.76 | TSHR (0.49) | DAOALDH1A1KDM4EHSD17B10NTRK1 | |
| SCHEMBL4716991 | 0.76 | DAO (0.58) | DAOKDM4EHSD17B10NTRK1IGF1R | |
| SCHEMBL31597601 | 0.74 | CA12 (0.72) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL12792523 | 0.74 | DAO (0.63) | DAOALDH1A1KDM4EHPGDNQO2 | |
| SCHEMBL7552092 | 0.72 | DAO (0.57) | DAOALDH1A1KDM4EHPGDCA12 | |
| SCHEMBL9836581 | 0.70 | MAT2A (0.61) | KDM4ENTRK1IGF1RFGFR1NTRK2 | |
| SCHEMBL25613278 | 0.70 | KDM4E (0.55) | KDM4EMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998004546-A1 | BENZIMIDAZOLE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-02-05 | — | — | WO | disclosed |