Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.58 |
| ▸ | HTR2A | P28223 | 11/20 | 0.58 |
| ▸ | HTR2B | P41595 | 10/20 | 0.58 |
| ▸ | PNMT | P11086 | 3/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12279234 | 1.00 | HTR2C (0.58) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| Hydrochloric Acid SCHEMBL23538187 | 0.98 | HTR2C (0.57) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| Hydrochloric Acid SCHEMBL29950615 | 0.98 | HTR2C (0.57) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| Hydrochloric Acid SCHEMBL29133384 | 0.84 | HTR2A (0.71) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| SCHEMBL13616552 | 0.80 | HTR2C (0.46) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL13630335 | 0.80 | HTR2C (0.46) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL6491638 | 0.76 | HTR2C (0.72) | HTR2CHTR2AHTR2BKCNH2 | |
| SCHEMBL14487997 | 0.75 | KDM1A (0.50) | HTR2CHTR2AHTR2BPNMTADRA2A | |
| Hydrochloric Acid SCHEMBL38652888 | 0.75 | HTR2C (0.42) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL6671284 | 0.74 | PNMT (0.56) | HTR2CHTR2AHTR2BPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120077042-A | 3A,4,5, 6-tetrahydro-1H-pyrazolo [3,4-C ] pyridin-7 (7 AH) -one derivatives as factor XIIa inhibitors | 卡尔维斯塔制药有限公司 | 2025-05-30 | — | — | CN | disclosed |