SCHEMBL14487997

SCHEMBL14487997

CC1Cc2cc(Br)ccc21

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.50
ADRA2A P08913 4/20 0.47
PNMT P11086 4/20 0.47
ADRA2B P18089 3/20 0.47
ADRA2C P18825 3/20 0.47
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
HTR2B P41595 1/20 0.44
OPRM1 P35372 2/20 0.42
OPRD1 P41143 1/20 0.42
OPRK1 P41145 1/20 0.42
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SRD5A1 P18405 1/20 0.37
KDM1B Q8NB78 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928975 0.81 ADRA2A (0.40) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL10024954 0.79 SRD5A1 (0.49) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL25831640 0.79 SRD5A1 (0.49) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL13948754 0.79 SRD5A1 (0.49) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL14488442 0.78 HTR2A (0.36) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL30016929 0.76 KDM1A (0.53) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL30558606 0.76 HTR2C (0.44) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL12270104 0.76 HTR2C (0.44) KDM1AADRA2APNMTADRA2BADRA2C
SCHEMBL18045112 0.76 ACHE (0.50) HTR2CCA1CA2SLC6A2SLC6A4
SCHEMBL13631383 0.76 PNMT (0.58) KDM1AADRA2APNMTADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573817-B2 Hole transporting compounds and compositions CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2020-02-25 US disclosed
EP-3195378-B1 HOLE TRANSPORTING COMPOSITIONS CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
US-10270037-B2 Polymers, monomers and methods of forming polymers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-04-23 US disclosed
EP-2755255-B1 Method and Compound CAMBRIDGE DISPLAY TECH LTD (GB) 2019-03-13 EP disclosed
EP-2755255-B1 Method and Compound CAMBRIDGE DISPLAY TECH LTD (GB) 2019-03-13 EP disclosed
EP-3195378-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS Cambridge Display Technology Limited (GB) 2017-07-26 EP disclosed
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-06 US disclosed
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-06 US disclosed
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-06 US disclosed
US-9269927-B2 Method and compound CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) 2016-02-23 US disclosed
US-9269927-B2 Method and compound CAMBRIDGE DISPLAY TECHNOLOGY, LTD. (GB) 2016-02-23 US disclosed
US-20140235800-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-08-21 US disclosed
US-20140235800-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-08-21 US disclosed
US-20140235800-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-08-21 US disclosed
US-20140193937-A1 METHOD AND COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-07-10 US disclosed
US-20140193937-A1 METHOD AND COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-07-10 US disclosed
US-20140193937-A1 METHOD AND COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-07-10 US disclosed
WO-2013005026-A2 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-01-10 WO disclosed
WO-2013005026-A2 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS PCNA, PARG, PARN KDM1A 1480/4885ADRA2A 1528/4885PNMT 657/4885
US-10270037-B2 Polymers, monomers and methods of forming polymers PCNA, PARG, PARN KDM1A 1480/4885ADRA2A 1528/4885PNMT 657/4885
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS SP1, NR0B1, C1S KDM1A 2395/4885ADRA2A 761/4885PNMT 1909/4885
US-10573817-B2 Hole transporting compounds and compositions SP1, NR0B1, C1S KDM1A 2395/4885ADRA2A 761/4885PNMT 1909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.