Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | CPN1 | P15169 | 2/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.36 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25961839 | 1.00 | PLA2G10 (0.40) | PLA2G10PLA2G2AJAK3CPN1CPB2 | |
| SCHEMBL22750389 | 0.95 | CPN1 (0.41) | PLA2G10PLA2G2AJAK3CPN1CPB2 | |
| SCHEMBL22750391 | 0.95 | CPN1 (0.41) | PLA2G10PLA2G2AJAK3CPN1CPB2 | |
| SCHEMBL25963075 | 0.91 | CPN1 (0.44) | JAK3CPN1CPB2CPA1 | |
| Hydrochloric Acid SCHEMBL25340503 | 0.89 | CPN1 (0.43) | JAK3CPN1CPB2CPA1 | |
| Hydrochloric Acid SCHEMBL25340501 | 0.89 | CPN1 (0.43) | JAK3CPN1CPB2CPA1 | |
| SCHEMBL25961558 | 0.88 | JAK3 (0.46) | PLA2G10PLA2G2AJAK3CPN1CPB2 | |
| SCHEMBL31599058 | 0.88 | JAK3 (0.46) | PLA2G10PLA2G2AJAK3CPN1CPB2 | |
| SCHEMBL25962534 | 0.87 | NPC1 (0.43) | JAK3 | |
| Hydrochloric Acid SCHEMBL25340173 | 0.87 | JAK3 (0.45) | PLA2G10PLA2G2AJAK3CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171399-A1 | PYRROLIDINE COMPOUNDS | ELI LILLY AND COMPANY | 2025-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171399-A1 | PYRROLIDINE COMPOUNDS | SDHA, GMPS, SDHB | PLA2G10 2878/4885PLA2G2A 4177/4885JAK3 874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.