⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25423925 | 0.72 | LOXL2 (0.47) | — | |
| SCHEMBL23005297 | 0.69 | UTRN (0.33) | — | |
| SCHEMBL30294954 | 0.69 | — | — | |
| SCHEMBL2244494 | 0.69 | — | — | |
| SCHEMBL677685 | 0.68 | LOX (0.47) | — | |
| SCHEMBL29518274 | 0.67 | — | — | |
| SCHEMBL22068158 | 0.67 | IDO1 (0.55) | — | |
| SCHEMBL1697620 | 0.67 | — | — | |
| SCHEMBL17165349 | 0.67 | — | — | |
| SCHEMBL2643794 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494971-B1 | SALTS OF ERK INHIBITORS | GENENTECH INC (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-111777594-B | Method for preparing a medicament | 基因泰克公司 | 2023-06-27 | — | — | CN | disclosed |
| US-11066389-B2 | Process for the manufacturing of medicaments | GENENTECH, INC. (US) | 2021-07-20 | — | — | US | disclosed |
| CN-112645927-A | Process for the preparation of a medicament | 基因泰克公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-106659721-B | Process for the preparation of a medicament | 基因泰克公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-111777594-A | Process for the preparation of a medicament | 基因泰克公司 | 2020-10-16 | — | — | CN | disclosed |
| US-20200190061-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2020-06-18 | — | — | US | disclosed |
| US-10611753-B2 | Process for the manufacturing of medicaments | GENENTECH, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| EP-3494971-A1 | SALTS OF ERK INHIBITORS | Genentech, Inc. (US) | 2019-06-12 | — | — | EP | disclosed |
| EP-3129025-B1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH INC (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20180134685-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2018-05-17 | — | — | US | disclosed |
| EP-3129025-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | Genentech, Inc. (US) | 2017-02-15 | — | — | EP | disclosed |
| US-20170022183-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2017-01-26 | — | — | US | disclosed |
| WO-2015154674-A1 | PROCESS FOR THE MANUFACTURING OF MEDICAMENTS | GENENTECH, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| EP-1546133-B1 | N-SUBSTITUTED-2-OXODIHYDROPYRIDINE DERIVATIVES AS NPY ANTAGONISTS | BANYU PHARMA CO LTD (JP) | 2010-03-17 | — | — | EP | disclosed |
| CN-100528864-C | N-substituted-2-oxodihydropyridine derivative | BANYU PHARMA CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1684954-A | N-substituted-2-oxodihydropyridine derivative | BANYU PHARMA CO LTD (JP) | 2005-10-19 | — | — | CN | disclosed |