Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139023 | 0.89 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3ADRB2CHRM1 | |
| SCHEMBL7227399 | 0.80 | IDO1 (0.38) | SLC6A4SLC6A2IDO1TDO2 | |
| SCHEMBL7235653 | 0.80 | IDO1 (0.38) | SLC6A4SLC6A2IDO1TDO2 | |
| SCHEMBL3784692 | 0.80 | CHRNA7 (0.39) | SLC6A4SLC6A2SLC6A3TDP1 | |
| SCHEMBL10488435 | 0.80 | CYP2A6 (0.32) | SLC6A4SLC6A2 | |
| SCHEMBL14889775 | 0.80 | ESR1 (0.37) | SLC6A2SLC6A3IDO1TDO2TSHR | |
| SCHEMBL151181 | 0.79 | IDO1 (0.44) | SLC6A4SLC6A2SLC6A3IDO1TSHR | |
| SCHEMBL3687682 | 0.79 | IDO1 (0.44) | SLC6A4SLC6A2SLC6A3IDO1TSHR | |
| SCHEMBL8924148 | 0.78 | HSD17B2 (0.38) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL333671 | 0.77 | CA12 (0.41) | TSHRMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605937-B1 | Antistatic resin composition | DAISO CO LTD (JP) | 1997-06-11 | — | — | EP | claimed |
| US-5401783-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1995-03-28 | — | — | US | claimed |
| US-5270351-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1993-12-14 | — | — | US | claimed |
| CN-104903359-A | Method for forming polymerization catalysts with controlled catalyst properties and use thereof in olefin polymerization | BASF SE | 2015-09-09 | — | — | CN | disclosed |
| CN-102186840-B | Piperidine compounds, pharmaceutical compositions containing the same and uses thereof | SK BIOPHARMACEUTICALS CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-104024282-A | Polymer composition containing oxidation-modifiable chlorinated propylene and method for producing same | TOYO BOSEKI | 2014-09-03 | — | — | CN | disclosed |
| CN-103189399-B | Method for producing chlorinated propylene-containing polymer | TOYO BOSEKI | 2014-08-27 | — | — | CN | disclosed |
| CN-103980184-A | Piperidine compounds, pharmaceutical composition comprising the same and its use | SK BIOPHARMACEUTICALS CO LTD | 2014-08-13 | — | — | CN | disclosed |
| CN-101228154-B | Tetracyclic tetrahydrofuran derivatives containing a cyclic amine side chain | JANSSEN PHARMACEUTICA NV | 2014-01-29 | — | — | CN | disclosed |
| US-8569267-B2 | Tetracyclic tetrahydrofuran derivatives containing cyclic amine side chain | JANSSEN PHARMACEUTICA, NV (BE) | 2013-10-29 | — | — | US | disclosed |
| CN-103189399-A | Method for producing chlorinated propylene-containing polymer | TOYO BOSEKI | 2013-07-03 | — | — | CN | disclosed |
| EP-0702015-A1 | Bicyclic oxazole and thiazole substituted ethers | SANDOZ LTD. (CH) | 1996-03-20 | — | — | EP | disclosed |
| WO-1995014690-A1 | MORPHOLINE DERIVATIVES AS DOPAMINE RECEPTOR SUBTYPE LIGANDS | MERCK SHARP & DOHME LIMITED (GB) | 1995-06-01 | — | — | WO | disclosed |
| US-5401783-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-5270351-A | Adhesion-promoting agents incorporating polyvalent cations | AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) | 1993-12-14 | — | — | US | disclosed |
| EP-0141324-B1 | ADHESION PROMOTING AGENT, PROCESS FOR ITS PREPARATION AND USE THEREOF ON COLLAGENEOUS MATERIAL | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
| US-4593054-A | Dentistry | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-03 | — | — | US | disclosed |
| EP-0141324-A2 | Adhesion promoting agent, process for its preparation and use thereof on collageneous material | BAYER AG (DE) | 1985-05-15 | — | — | EP | disclosed |
| US-4237132-A | ARTERIOSCLEROSIS, ANTICHOLESTEROL, ANTILIPEMIC | NIPPON SHINYAKU CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-3953604-A | INHALATION, ANTI-ASTHMA | MILES LABORATORIES, INC. (US) | 1976-04-27 | — | — | US | disclosed |