Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151181 | 1.00 | IDO1 (0.44) | IDO1CHRM2CHRM4CHRM5CHRM1 | |
| Ethylene Glycol SCHEMBL8153345 | 0.91 | CHRM2 (0.38) | IDO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7867600 | 0.88 | EPHX1 (0.41) | IDO1EPHX1 | |
| Phthalic Anhydride SCHEMBL10391291 | 0.86 | TDP1 (0.45) | IDO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28635190 | 0.85 | LTA4H (0.41) | TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7294198 | 0.85 | EPHX1 (0.55) | IDO1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL27376966 | 0.85 | IDO1 (0.42) | IDO1CHRM2CHRM4CHRM5CHRM1 | |
| Acrylic Acid SCHEMBL1344846 | 0.85 | SLC6A3 (0.36) | IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8045688 | 0.84 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8847061 | 0.84 | MGLL (0.42) | CHRM2CHRM5CHRM3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1616852-B1 | PROCESS FOR PRODUCING BETA-HYDROXYESTER | DAISO CO LTD (JP) | 2010-08-11 | — | — | EP | disclosed |
| US-7256305-B2 | Process for producing β-hydroxyester | DAISO CO., LTD. (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20060122419-A1 | Esterification of an epoxide, an alcohol and carbon monoxide in the presence of a cobalt carbonyl compound as catalyst and a cocatalyst of substituted pyridine | DAISO CO., LTD. (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1616852-A1 | PROCESS FOR PRODUCING BETA-HYDROXYESTER | DAISO CO., LTD. (JP) | 2006-01-18 | — | — | EP | disclosed |
| EP-0328251-B1 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | ICI PLC (GB) | 1994-04-13 | — | — | EP | disclosed |
| EP-0426804-B1 | 2-(2-HYDROXY-3-PHENOXYPROPYLAMINO)-ETHOXYBENZENE DERIVATIVES | ICI PLC (GB) | 1994-01-19 | — | — | EP | disclosed |
| EP-0426804-A1 | 2-(2-HYDROXY-3-PHENOXYPROPYLAMINO)-ETHOXYBENZENE DERIVATIVES. | ICI PLC (GB) | 1991-05-15 | — | — | EP | disclosed |
| US-4999377-A | 2-(2-hydroxy-3-phenoxypropylamino)ethylphenoxyacetamide compounds; dietetics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-03-12 | — | — | US | disclosed |
| WO-1990013535-A1 | COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-15 | — | — | WO | disclosed |
| CN-1005711-B | Preparation method of phenoxypropanolamine compounds | 弗·哈夫曼-拉罗彻公司 | 1989-11-08 | — | — | CN | disclosed |
| EP-0328251-A2 | 2-(2-Hydroxy-3-phenoxypropylamino)ethylphenoxyacetamides and processes and intermediates for their preparation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-16 | — | — | EP | disclosed |
| CN-85101280-A | Benzene oxygen propanol amine compounds | — | 1987-01-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122419-A1 | Esterification of an epoxide, an alcohol and carbon monoxide in the presence of a cobalt carbonyl compound as catalyst and a cocatalyst of substituted pyridine | CYP2E1, CBR1, ADH1A | IDO1 1302/4885CHRM2 871/4885CHRM4 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.