Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.38 |
| ▸ | TACR1 | P25103 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599275 | 0.90 | L3MBTL1 (0.43) | MAPTNR1H2NR1H3TACR1L3MBTL1 | |
| SCHEMBL28622444 | 0.87 | KCNH2 (0.40) | KCNH2HSD11B1 | |
| SCHEMBL31599278 | 0.80 | NR1H3 (0.41) | MAPTNR1H2NR1H3TACR1 | |
| SCHEMBL31599268 | 0.79 | LMNA (0.45) | MAPTNR1H2NR1H3TACR1L3MBTL1 | |
| SCHEMBL31599262 | 0.79 | POLB (0.38) | NR1H2NR1H3TACR1 | |
| SCHEMBL28624276 | 0.77 | LMNA (0.49) | TACR1L3MBTL1RORC | |
| SCHEMBL5363568 | 0.76 | NR1H2 (0.43) | MAPTNR1H2NR1H3RORC | |
| SCHEMBL5363572 | 0.76 | NR1H2 (0.43) | MAPTNR1H2NR1H3RORC | |
| SCHEMBL31599294 | 0.75 | TACR1 (0.42) | MAPTNR1H2NR1H3TACR1RORC | |
| SCHEMBL30075118 | 0.75 | TACR1 (0.42) | MAPTNR1H2NR1H3TACR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072546-B | Five-membered heteroaromatic derivative and preparation method and application thereof | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | CN | disclosed |