Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.37 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851435 | 0.79 | KDM4E (0.53) | P2RX7KDM4EALDH1A1MAPTKCNQ3 | |
| SCHEMBL18068216 | 0.78 | GABRP (0.47) | KDM4EALDH1A1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL21306488 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1POLQKCNQ3KCNQ2 | |
| SCHEMBL30964013 | 0.78 | GABRP (0.47) | KDM4EALDH1A1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL30845500 | 0.78 | SMN1; SMN2 (0.42) | KDM4EALDH1A1POLQKCNQ3KCNQ2 | |
| SCHEMBL18725404 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTPOLQKCNQ3 | |
| SCHEMBL30770791 | 0.77 | HSP90AB1 (0.37) | KDM4EALDH1A1MAPTPOLQKCNQ3 | |
| SCHEMBL27334085 | 0.77 | HSP90AB1 (0.37) | KDM4EALDH1A1MAPTPOLQKCNQ3 | |
| SCHEMBL25074121 | 0.77 | NNMT (0.43) | P2RX7KDM4EALDH1A1MAPTOGG1 | |
| SCHEMBL30043246 | 0.77 | NNMT (0.43) | P2RX7KDM4EALDH1A1MAPTOGG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109540-A1 | MACROCYCLIC COMPOUNDS AS KIF18A INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-05-30 | — | — | WO | disclosed |