Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16431711 | 0.79 | HPGD (0.43) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL31600919 | 0.79 | MEN1 (0.46) | LMNAL3MBTL1MEN1KMT2APKM | |
| Hydrochloric Acid SCHEMBL31600226 | 0.77 | MAPT (0.44) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL25186788 | 0.77 | MAPT (0.39) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL16432160 | 0.76 | L3MBTL1 (0.41) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL31600579 | 0.76 | HTR2A (0.40) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL10967724 | 0.76 | LMNA (0.57) | LMNAL3MBTL1MEN1KMT2AHSD17B10 | |
| SCHEMBL16432256 | 0.71 | GRM5 (0.37) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL16431781 | 0.71 | GRM5 (0.37) | LMNAL3MBTL1MEN1KMT2APKM | |
| SCHEMBL16431851 | 0.71 | HSD17B10 (0.48) | LMNAL3MBTL1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |