Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31600546 | 0.98 | ALDH1A1 (0.34) | ALDH1A1KDM4ENPC1RAB9ACASP1 | |
| SCHEMBL31600135 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4ENPC1RAB9ACASP1 | |
| SCHEMBL31600077 | 0.71 | ADORA3 (0.31) | ALDH1A1KDM4EHPGD | |
| SCHEMBL21166828 | 0.69 | ALDH1A1 (0.38) | ALDH1A1KDM4ENPC1RAB9ACASP1 | |
| SCHEMBL31600862 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL31600208 | 0.68 | ALDH1A1 (0.36) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2182645 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL16714643 | 0.65 | ADORA2A (0.36) | ALDH1A1KDM4ENPC1RAB9ACASP1 | |
| Hydrochloric Acid SCHEMBL18662690 | 0.65 | ADORA2A (0.36) | ALDH1A1KDM4ENPC1RAB9ACASP1 | |
| SCHEMBL31600703 | 0.64 | MAP4K4 (0.41) | ALDH1A1KDM4ENPC1RAB9ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |