Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31600662 | 0.85 | ESR2 (0.38) | UCHL1USP30HSP90AA1HSP90AB1GPR119 | |
| SCHEMBL31514682 | 0.78 | POLB (0.37) | UCHL1GPR119ESR2STSPOLB | |
| SCHEMBL30746650 | 0.77 | UCHL1 (0.47) | UCHL1USP30GPR119POLBCHRNA7 | |
| SCHEMBL21855821 | 0.77 | UCHL1 (0.47) | UCHL1USP30GPR119POLBCHRNA7 | |
| SCHEMBL21166288 | 0.77 | GPR119 (0.39) | UCHL1USP30HSP90AA1HSP90AB1GPR119 | |
| SCHEMBL31600449 | 0.75 | NR1H2 (0.36) | UCHL1USP30HSP90AA1HSP90AB1GPR119 | |
| SCHEMBL21143651 | 0.75 | MTOR (0.42) | — | |
| SCHEMBL31127096 | 0.75 | MTOR (0.42) | — | |
| SCHEMBL18181095 | 0.74 | ESR2 (0.44) | HSP90AA1HSP90AB1GPR119ESR2POLB | |
| SCHEMBL30513272 | 0.74 | POLB (0.41) | UCHL1GPR119ESR2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |