Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.40 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22661081 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22645710 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22645711 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL23036707 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL30279188 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL28803526 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL31500135 | 0.86 | GAA (0.48) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL28537514 | 0.81 | BTK (0.54) | KMT2AGAANFKB1NFKB2RELA | |
| SCHEMBL28540918 | 0.81 | BTK (0.54) | KMT2AGAANFKB1NFKB2RELA | |
| SCHEMBL30596812 | 0.80 | BTK (0.47) | KMT2AGAANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111464-A1 | JAK2 V617F INHIBITORS AND METHODS OF USE THEREOF | RAYTHERA, INC. (US) | 2025-05-30 | — | — | WO | disclosed |