Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279188 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22661081 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22645711 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL22645710 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL31601434 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL23036707 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL31008916 | 0.87 | GAA (0.45) | ALDH1A1KMT2AGAABTKNFKB1 | |
| SCHEMBL11888286 | 0.86 | KMT2A (0.48) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL29317638 | 0.84 | KMT2A (0.44) | ALDH1A1KMT2AMEN1TSHRGAA | |
| SCHEMBL23274580 | 0.83 | BTK (0.57) | ALDH1A1KMT2AGAABTKNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492164-B2 | Fluorine substituted cyclohexene analogues of gamma-aminobutyric acid (GABA) | NORTHWESTERN UNIVERSITY (US) | 2025-12-09 | — | — | US | disclosed |
| US-20240239738-A1 | (S)-3-AMINO-4-(DIFLUOROMETHYLENE)CYCLOHEXENE AND CYCLOHEXANE CARBOXYLIC ACID AND USES THEREOF AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE (hOAT) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-07-18 | — | — | US | disclosed |
| US-20230107230-A1 | FLUORINE SUBSTITUTED CYCLOHEXENE ANALOGUES OF GAMMA- AMINOBUTYRIC ACID (GABA) | NORTHWESTERN UNIVERSITY | 2023-04-06 | — | — | US | disclosed |
| EP-4048654-A1 | FLUORINE SUBSTITUTED CECLOHEXENE ANALOGOUES OF GAMMA-AMINOBUTYRIC ACID (GABA) | Northwestern University (US) | 2022-08-31 | — | — | EP | disclosed |
| CN-114867714-A | Fluoro substituted cyclohexene analogues of gamma-aminobutyric acid (GABA) | 西北大学 | 2022-08-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230107230-A1 | FLUORINE SUBSTITUTED CYCLOHEXENE ANALOGUES OF GAMMA- AMINOBUTYRIC ACID (GABA) | OAT, GABBR1, SLC1A2 | ALDH1A1 287/4885KMT2A 3571/4885MEN1 4185/4885 |
| US-12492164-B2 | Fluorine substituted cyclohexene analogues of gamma-aminobutyric acid (GABA) | OAT, GABBR1, SLC1A2 | ALDH1A1 287/4885KMT2A 3571/4885MEN1 4185/4885 |
| US-20240239738-A1 | (S)-3-AMINO-4-(DIFLUOROMETHYLENE)CYCLOHEXENE AND CYCLOHEXANE CARBOXYLIC ACID AND USES THEREOF AS SELECTIVE INACTIVATORS OF HUMAN ORNITHINE AMINOTRANSFERASE (hOAT) | AADAT, DLAT, OAT | ALDH1A1 115/4885KMT2A 625/4885MEN1 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.