SCHEMBL31601448

SCHEMBL31601448

Cn1c(=O)n(C2CCC(=O)NC2=O)c2ccc(OCCCCCCC(=O)O)cc21

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 12/20 0.56
▸ DDB1 Q16531 10/20 0.56
▸ PDE3B Q13370 6/20 0.46
▸ PDE3A Q14432 6/20 0.46
▸ P2RY12 Q9H244 4/20 0.46
▸ PDE2A O00408 3/20 0.44
▸ FFAR1 O14842 1/20 0.37
▸ PPARG P37231 1/20 0.37
▸ PPARD Q03181 1/20 0.37
▸ PPARA Q07869 1/20 0.37
▸ DRD2 P14416 1/20 0.37
▸ DRD4 P21917 1/20 0.37
▸ DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31601585 0.88 CRBN (0.52) CRBNDDB1PDE3BPDE3AP2RY12
SCHEMBL30938883 0.88 DDB1 (0.59) CRBNDDB1
SCHEMBL23842393 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL22526737 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL21069854 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL25123826 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL30990754 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL25123832 0.86 CRBN (0.64) CRBNDDB1
SCHEMBL23842050 0.85 CRBN (0.66) CRBNDDB1
SCHEMBL30919905 0.84 DDB1 (0.58) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 — — WO disclosed
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