E626

SCHEMBL31601933

Cc1cn([C@@H]2O[C@H](CO)[C@@H](OP(=O)(O)O)[C@H]2O)c(=O)[nH]c1=O.[2H]n1c(N)nc(=O)c2ncn([C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]3O)c21

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	DTYMK	P23919	4/20	0.51

▸	DNPH1	O43598	1/20	0.50

▸	F2	P00734	1/20	0.47

▸	RNASEL	Q05823	5/20	0.47

▸	IMPDH2	P12268	4/20	0.47

▸	IMPDH1	P20839	1/20	0.47

▸	NT5E	P21589	1/20	0.46

▸	TAS1R3	Q7RTX0	1/20	0.46

▸	TAS1R1	Q7RTX1	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4366552	0.79	ADORA1 (0.55)	DNPH1NT5ETAS1R3TAS1R1
SCHEMBL4366567	0.79	ADORA1 (0.55)	DNPH1NT5ETAS1R3TAS1R1
SCHEMBL1904388	0.78	TYMP (0.59)	DNPH1
SCHEMBL25895055	0.78	DTYMK (0.55)	DTYMKF2RNASEL
SCHEMBL25895053	0.78	DTYMK (0.67)	DTYMKDNPH1RNASELTAS1R3TAS1R1
E626 SCHEMBL10325122	0.78	P2RY2 (0.56)	DTYMKF2RNASELIMPDH2IMPDH1
E626 SCHEMBL94794	0.78	TAS1R3 (0.61)	DNPH1IMPDH2IMPDH1NT5ETAS1R3
E626 SCHEMBL4360700	0.78	TAS1R3 (0.61)	DNPH1IMPDH2IMPDH1NT5ETAS1R3
E626 SCHEMBL4361871	0.78	TAS1R3 (0.61)	DNPH1IMPDH2IMPDH1NT5ETAS1R3
E626 SCHEMBL6036980	0.77	DTYMK (0.68)	DTYMKF2IMPDH2IMPDH1NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-120077134-A	APOC 3-targeted polynucleic acid molecule and application thereof	靖因药业有限公司	2025-05-30	—	—	CN	disclosed