Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31602195 | 0.82 | KMT2A (0.54) | KMT2AMEN1MAPTLMNAGFER | |
| SCHEMBL25371875 | 0.75 | KMT2A (0.60) | KMT2AMEN1MAPTLMNAGFER | |
| SCHEMBL4666246 | 0.74 | ROCK1 (0.62) | KMT2AMEN1MAPTLMNAHPGD | |
| Trinitrophenol SCHEMBL10532350 | 0.72 | MEN1 (0.47) | KMT2AMEN1MAPTLMNAGFER | |
| SCHEMBL30488025 | 0.72 | RAB9A (0.69) | KMT2AMEN1MAPTABCG2ROCK1 | |
| SCHEMBL15305715 | 0.72 | RAB9A (0.69) | KMT2AMEN1MAPTABCG2ROCK1 | |
| SCHEMBL2409631 | 0.70 | MAPT (0.53) | KMT2AMEN1MAPTLMNAGFER | |
| Diphenylamine SCHEMBL6373876 | 0.70 | ALOX12 (0.79) | KMT2AMEN1MAPTLMNAGFER | |
| SCHEMBL913813 | 0.70 | MEN1 (1.00) | KMT2AMEN1MAPTLMNAHPGD | |
| SCHEMBL27927838 | 0.70 | MAPT (0.79) | KMT2AMEN1MAPTLMNAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025109475-A1 | SHP-1 AGONISTS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-05-30 | — | — | WO | disclosed |