SCHEMBL31604497

SCHEMBL31604497

CC(C)(C)[Si](C)(C)OCC1CCN(N)C1=O

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DUT P33316 3/20 0.36
FKBP1A P62942 1/20 0.31
TOP2A P11388 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6658119 0.75 PDE4A (0.38) FKBP1A
SCHEMBL6533522 0.74 DUT (0.33) DUT
SCHEMBL29106951 0.73
SCHEMBL10433360 0.70 DUT (0.35) DUTFKBP1ATOP2A
SCHEMBL28408929 0.70 DUT (0.35) DUTFKBP1ATOP2A
SCHEMBL31009085 0.70 DUT (0.35) DUTFKBP1ATOP2A
SCHEMBL14769248 0.69 FKBP1A (0.32) FKBP1A
SCHEMBL18305983 0.69 DUT (0.37) DUTFKBP1ATOP2A
SCHEMBL8781847 0.69 CA1 (0.38) DUTFKBP1ATOP2A
SCHEMBL30065237 0.69 DUT (0.33) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111415-A1 TRPM3-MODULATING INDOLIZINE DERIVATIVES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-05-30 WO disclosed