Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31604515 | 0.74 | TDP1 (0.42) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL31604501 | 0.73 | MAPT (0.44) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL31604507 | 0.71 | CXCR2 (0.41) | CXCR2HSD11B1CXCR1CA1CA2 | |
| SCHEMBL31604508 | 0.70 | MAPT (0.41) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL10073218 | 0.70 | CYP3A4 (0.49) | ALDH1A1MAPTMEN1KMT2ACXCR2 | |
| SCHEMBL31604510 | 0.70 | KDM4E (0.40) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL31604502 | 0.70 | PABPC1 (0.45) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL1928327 | 0.70 | STS (0.65) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL21580842 | 0.69 | ADORA1 (0.43) | ALDH1A1KDM4EMAPTTDP1CXCR2 | |
| SCHEMBL364294 | 0.69 | KMT2A (0.44) | ALDH1A1KDM4EMEN1KMT2ACXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111415-A1 | TRPM3-MODULATING INDOLIZINE DERIVATIVES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-05-30 | — | — | WO | disclosed |