Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.30 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21580842 | 0.72 | ADORA1 (0.43) | CXCR2HSD11B1 | |
| SCHEMBL21580845 | 0.71 | CXCR2 (0.36) | CXCR2CXCR1HSD11B1DRD2DRD3 | |
| SCHEMBL31604514 | 0.71 | ALDH1A1 (0.40) | CXCR2CXCR1HSD11B1CA1CA2 | |
| SCHEMBL576035 | 0.70 | CA2 (0.50) | CXCR2CXCR1HSD11B1CA1CA2 | |
| SCHEMBL840762 | 0.70 | KMT2A (0.50) | CXCR2CXCR1CA1CA2 | |
| SCHEMBL1992738 | 0.68 | SCN5A (0.38) | CXCR2CXCR1HSD11B1CA1CA2 | |
| SCHEMBL31604511 | 0.68 | CA2 (0.38) | CA1CA2DRD1 | |
| SCHEMBL3668194 | 0.66 | STS (0.60) | CXCR2CXCR1HSD11B1 | |
| SCHEMBL5565709 | 0.66 | ALDH1A1 (0.51) | CXCR2CXCR1HSD11B1CA1CA2 | |
| SCHEMBL6935157 | 0.65 | CXCR2 (0.47) | CXCR2CXCR1HSD11B1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111415-A1 | TRPM3-MODULATING INDOLIZINE DERIVATIVES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2025-05-30 | — | — | WO | disclosed |