SCHEMBL3160503

SCHEMBL3160503

CCCCCCCCCC(C)(C)N(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.40
L3MBTL1 Q9Y468 1/20 0.36
MAPT P10636 1/20 0.35
HTR1B P28222 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
KDM4E B2RXH2 3/20 0.35
NPC1 O15118 3/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 3/20 0.35
HTT P42858 3/20 0.35
RAB9A P51151 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
NPSR1 Q6W5P4 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2239450 0.99 SIGMAR1 (0.40) SIGMAR1L3MBTL1MAPTHTR1BCNR1
SCHEMBL2187826 0.83 NPC1 (0.41) SIGMAR1L3MBTL1CNR1CNR2NPC1
SCHEMBL2185586 0.83 NPC1 (0.41) SIGMAR1L3MBTL1CNR1CNR2NPC1
SCHEMBL44716 0.82 NPC1 (0.38) SIGMAR1L3MBTL1MAPTCNR1CNR2
SCHEMBL871746 0.78 SIGMAR1 (0.44) SIGMAR1L3MBTL1MAPTKDM4EALDH1A1
SCHEMBL23251118 0.77 SIGMAR1 (0.38) SIGMAR1L3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL5612358 0.77 SIGMAR1 (0.48) SIGMAR1L3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL28438061 0.76 KDM4E (0.40) L3MBTL1MAPTCNR1CNR2KDM4E
SCHEMBL3174758 0.75 SIGMAR1 (0.42) SIGMAR1L3MBTL1HTR1BNPC1ALDH1A1
SCHEMBL9619175 0.75 SIGMAR1 (0.42) SIGMAR1L3MBTL1HTR1BNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642175-B Marine diesel engine cylinder lubricating oil composition 雪佛龙奥伦耐技术有限责任公司 2023-07-18 CN disclosed
CN-107207983-B Use of a lubricating composition 国际壳牌研究有限公司 2022-11-18 CN disclosed
CN-110546243-B Lubricating composition 国际壳牌研究有限公司 2022-09-23 CN disclosed
CN-107001978-B Method for reducing low speed pre-ignition 国际壳牌研究有限公司 2022-07-19 CN disclosed
CN-111094525-B Lubricating oil composition for internal combustion engine 国际壳牌研究有限公司 2022-06-10 CN disclosed
CN-108431188-B Lubricating oil composition for diesel engines 国际壳牌研究有限公司 2021-05-28 CN disclosed
CN-107207982-B Organic friction modifiers 亨斯迈石油化学有限责任公司 2020-07-03 CN disclosed
CN-111094525-A Lubricating oil composition for internal combustion engine 国际壳牌研究有限公司 2020-05-01 CN disclosed
CN-110546243-A Lubricating composition SHELL INT RESEARCH 2019-12-06 CN disclosed
CN-104619818-A Lubricating oil composition for internal combustion engines SHELL INT RESEARCH 2015-05-13 CN disclosed
CN-104603250-A Lubricating oil composition for internal combustion engine SHELL INT RESEARCH 2015-05-06 CN disclosed
US-20100009878-A1 LUBRICATING OIL COMPOSITION SHOWA SHELL SEKIYU K.K. (JP) 2010-01-14 US disclosed
EP-2092046-A1 LUBRICATING OIL COMPOSITION Showa Shell Sekiyu K. K. (JP) 2009-08-26 EP disclosed
WO-2008090179-A1 LUBRICATING OIL COMPOSITION SHOWA SHELL SEKIYU K.K. (JP) 2008-07-31 WO disclosed