SCHEMBL871746

SCHEMBL871746

CC(C)(C)CC(C)(C)N(c1ccccc1)c1cccc2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 10/20 0.44
L3MBTL1 Q9Y468 1/20 0.37
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.33
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
PER2 O15055 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
CRY1 Q16526 1/20 0.33
CRY2 Q49AN0 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15496372 0.81 SIGMAR1 (0.50) SIGMAR1L3MBTL1SLC6A2SLC6A4CYP1A2
SCHEMBL44715 0.80 MEN1 (0.38) L3MBTL1SLC6A2CYP2D6CYP2C19ALDH1A1
SCHEMBL2239450 0.79 SIGMAR1 (0.40) SIGMAR1L3MBTL1MAPT
SCHEMBL252529 0.79 ALDH1A1 (0.33) CYP2C19ALDH1A1KDM4EMEN1KMT2A
SCHEMBL23184557 0.78 SIGMAR1 (0.47) SIGMAR1L3MBTL1SLC6A2SLC6A4CYP1A2
SCHEMBL3160503 0.78 SIGMAR1 (0.40) SIGMAR1L3MBTL1CYP1A2CYP2D6CYP2C19
SCHEMBL3450294 0.77 ESR1 (0.31) CYP2C19MEN1KMT2A
SCHEMBL23251118 0.77 SIGMAR1 (0.38) SIGMAR1L3MBTL1SLC6A2SLC6A4CYP2C19
SCHEMBL29048064 0.76 SIGMAR1 (0.43) SIGMAR1L3MBTL1SLC6A2SLC6A4CYP1A2
SCHEMBL6931503 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 748 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025126139-A1 LUBRICANT COMPOSITIONS CONTAINING AROMATIC AMINES FOR REDUCED ABNORMAL COMBUSTION EVENTS IN HYDROGEN FUELED ENGINES INFINEUM INTERNATIONAL LIMITED (GB) 2025-06-19 WO claimed
CN-115287111-A Ether-based lubricant compositions, methods and uses 卡斯特罗尔有限公司 2022-11-04 CN claimed
CN-110462011-B Ether-based lubricant compositions, methods and uses 卡斯特罗尔有限公司 2022-05-13 CN claimed
EP-1137747-B1 LUBRICANT COMPOSITIONS COMPRISING MULTIPLE ANTIOXIDANTS CHEMTURA CORP (US) 2008-07-23 EP claimed
EP-0721979-B1 Stabilized lubricant compositions CIBA SC HOLDING AG (CH) 2002-04-17 EP claimed
US-5580482-A CONTAINING AN N,N-DISUBSTITUTED AMINOMETHYL-1,2,4-TRIAZOLE OR AN N,N-DISUBSTITUTED AMINOMETHYLBENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1996-12-03 US claimed
EP-0721979-A2 Stabilized lubricant compositions CIBA-GEIGY AG (CH) 1996-07-17 EP claimed
US-5336420-A Reaction product of mercaptoheterocyclic compounds with quaternary ammonium salts and hydrocarbon-substituted succinic anhydride MOBIL OIL CORPORATION (US) 1994-08-09 US claimed
US-4216100-A FRO GAS TURBINE ENGINES TEXACO INC. (US) 1980-08-05 US claimed
US-RE28805-E Lubricants containing amine antioxidants MOBIL OIL CORPORATION (US) 1976-05-11 US claimed
WO-2026099357-A1 LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LIMITED (GB) 2026-05-15 WO disclosed
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS INFINEUM INTERNATIONAL LTD (GB) 2026-05-14 US disclosed
EP-3947611-B1 A MIDDLE-PRESSURE POLYMERIZATION PROCESS FOR LIQUID ETHYLENE COPOLYMERS BASF SE (DE) 2026-05-06 EP disclosed
EP-4596662-B1 AMINE CONTAINING POLYMERS AND LUBRICANT COMPOSITIONS INCLUDING SUCH POLYMERS AND METHODS OF USING THEREOF INFINEUM INT LTD (GB) 2026-04-29 EP disclosed
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels ExxonMobil Technology and Engineering Company (US) 2026-04-28 US disclosed
US-4320018-A ALPHATIC ESTER BASE LUBRICATN CONTAINING DIARYLAMINE, HYDROXY ANTHRAQUIONE HYDROCARBYL PHOSPHATE ESTER AND DIALKYL DISULFIDE TEXACO INC. (US) 1982-03-16 US disclosed
US-4248721-A MIXTURE OF CARBOXYLIC PENTAERYTHRITOL ESTER, PHENYL NAPHTHYLAMINE, DIPHENYLAMINE, POLYHYDROXYANTHRAQUINONE, PHOSPHATE ESTER, THIADIAZOLE DERIVATIVE TEXACO INC. (US) 1981-02-03 US disclosed
US-4188298-A ACYCLIC ESTER, ARYLAMINES, SULFIDES AND ARYL PHOSPHATES, OXIDATIVE STABILITY TEXACO INC. (US) 1980-02-12 US disclosed
US-RE28805-E Lubricants containing amine antioxidants MOBIL OIL CORPORATION (US) 1976-05-11 US disclosed
US-3879307-A Organic compositions containing synergistic antioxidant mixtures MOBIL OIL CORP 1975-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612880-B2 Engine lubricant optimization for advanced sustainable fuels TST, TCF4, MLLT1 SIGMAR1 3792/4885L3MBTL1 138/4885SLC6A2 2967/4885
US-20260132352-A1 LUBRICATING OIL COMPOSITIONS SFN, DGKG, TAF1 SIGMAR1 225/4885L3MBTL1 3330/4885SLC6A2 4641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.