Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31607286 | 1.00 | ALDH1A1 (0.40) | ALDH1A1KMT2ACYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL31607334 | 0.82 | ABL1 (0.36) | ALDH1A1KMT2ACYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL31474310 | 0.81 | KMT2A (0.47) | ALDH1A1KMT2AHCAR3POLBMAPT | |
| SCHEMBL29215568 | 0.81 | KMT2A (0.47) | ALDH1A1KMT2AHCAR3POLBMAPT | |
| SCHEMBL31607362 | 0.78 | KMT2A (0.51) | ALDH1A1KMT2AHCAR3MAPTTTR | |
| SCHEMBL31607343 | 0.78 | KMT2A (0.51) | ALDH1A1KMT2AHCAR3MAPTTTR | |
| SCHEMBL25380351 | 0.78 | ALDH1A1 (0.38) | ALDH1A1KMT2ACYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL30979300 | 0.76 | L3MBTL1 (0.39) | ALDH1A1KMT2ACYP3A4L3MBTL1CYP1A2 | |
| SCHEMBL31607308 | 0.76 | NPSR1 (0.39) | ALDH1A1KMT2ACYP2C19POLBMAPT | |
| SCHEMBL31607350 | 0.75 | TSHR (0.34) | ALDH1A1KMT2AL3MBTL1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613752-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-08-28 | — | — | US | disclosed |
| CN-120092010-A | Polycyclic poly (ADP-ribose) polymerase selective inhibitors | 轩竹生物科技股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | PARP1, PARP11, PARP2 | ALDH1A1 1101/4885KMT2A 961/4885CYP3A4 1409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.