SCHEMBL31607499

SCHEMBL31607499

[2H]C([2H])([2H])N1C(=O)CN(Cc2ccc(-c3nc(C(F)(F)F)cn3C)cc2)c2nc(Cl)ncc21

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30693835 0.87 USP1 (0.48) USP1
SCHEMBL27088162 0.87 USP1 (0.48) USP1
SCHEMBL27088190 0.86 USP1 (0.46) USP1
SCHEMBL30032078 0.85 USP1 (0.44) USP1
SCHEMBL27088242 0.85 USP1 (0.44) USP1
SCHEMBL27088316 0.84 USP1 (0.41) USP1
SCHEMBL30033712 0.84 USP1 (0.41) USP1
SCHEMBL31607477 0.80 USP1 (0.65) USP1
SCHEMBL30693863 0.80 USP1 (0.45) USP1
SCHEMBL27088186 0.80 USP1 (0.45) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120092007-A Heterocyclopyrimidine compound, pharmaceutical composition and application thereof 海南先声再明医药股份有限公司 2025-06-03 — — CN disclosed
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