SCHEMBL31607945

SCHEMBL31607945

CC(C)(C)OC(=O)N1CCC(N2CCN(c3cccc(C4CCC(=O)NC4=O)c3)CC2)CC1

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 11/20 0.58
▸ CRBN Q96SW2 11/20 0.58
▸ GPR119 Q8TDV5 6/20 0.50
▸ USP30 Q70CQ3 1/20 0.46
▸ MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21876868 0.93 DDB1 (0.63) DDB1CRBNGPR119MAPT
SCHEMBL30643599 0.91 DDB1 (0.54) DDB1CRBNGPR119USP30
SCHEMBL31134647 0.89 DDB1 (0.59) DDB1CRBNGPR119MAPT
SCHEMBL30768973 0.88 DDB1 (0.59) DDB1CRBNGPR119USP30
SCHEMBL30643616 0.88 DDB1 (0.61) DDB1CRBNMAPT
SCHEMBL31342602 0.88 DDB1 (0.54) DDB1CRBNGPR119USP30MAPT
SCHEMBL30830715 0.85 DDB1 (0.58) DDB1CRBNGPR119USP30
SCHEMBL31487408 0.85 DDB1 (0.58) DDB1CRBNGPR119USP30
SCHEMBL30965512 0.85 DDB1 (0.58) DDB1CRBNGPR119USP30
SCHEMBL30643569 0.85 DDB1 (0.59) DDB1CRBNGPR119MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120092003-A CDK protein degrading agents, pharmaceutical compositions and therapeutic uses 拜欧斯瑞克斯公司 2025-06-03 — — CN disclosed
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