Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.86 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.65 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.65 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.47 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL30032426 | 0.93 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL30323638 | 0.93 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL27409567 | 0.93 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL8568063 | 0.93 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL8568060 | 0.93 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL25241602 | 0.93 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL2478164 | 0.93 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL175940 | 0.93 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL20362356 | 0.93 | — | — | |
| D-Leucine SCHEMBL42012 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276895-B1 | METHOD FOR THE IDENTIFICATION OF ACTIVE SITE PROTEASE INACTIVATORS | UNIV GEORGIA (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1379634-A1 | ACTIVE SITE INACTIVATORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2004-01-14 | — | — | EP | disclosed |
| US-20030077653-A1 | Method for the identification of active site protease inactivators | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2003-04-24 | — | — | US | disclosed |
| WO-2002086115-A1 | ACTIVE SITE INACTIVATORS | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2002-10-31 | — | — | WO | disclosed |