Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25431166 | 1.00 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL19114247 | 0.86 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL30159589 | 0.79 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL23535827 | 0.79 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL30595155 | 0.73 | CYP2A6 (0.52) | CYP2A6 | |
| SCHEMBL30552801 | 0.71 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL25434391 | 0.71 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL2550820 | 0.70 | CYP2A6 (0.58) | CYP2A6 | |
| SCHEMBL29641226 | 0.70 | CYP2A6 (0.58) | CYP2A6 | |
| SCHEMBL25373058 | 0.70 | GPR35 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4482583-B1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2026-04-01 | — | — | EP | disclosed |
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2025-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179066-A1 | ZWITTERIONIC ANTIBACTERIAL COMPOUNDS | MRPL21, WIZ, CFTR | CYP2A6 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.