SCHEMBL31609727

SCHEMBL31609727

CCOc1ccc(F)c(C(N)=O)c1F

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.46
TSHR P16473 1/20 0.44
PARP10 Q53GL7 1/20 0.42
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CREBBP Q92793 1/20 0.41
FGFR2 P21802 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
TNKS2 Q9H2K2 1/20 0.39
MAP2K1 Q02750 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
KDM1A O60341 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17712588 0.87 MAPT (0.46) USP2SMN1; SMN2HSD17B10ALDH1A1LMNA
SCHEMBL12432971 0.85 TNKS2 (0.34) MAPK1PARP10LMNAHTTTNKS2
SCHEMBL4398112 0.85 TSHR (0.45) TSHRNPC1USP2RAB9ASMN1; SMN2
SCHEMBL202528 0.83 MEN1 (0.54) ALDH1A1LMNAMEN1KMT2A
SCHEMBL203389 0.83 MEN1 (0.54) ALDH1A1LMNAMEN1KMT2A
SCHEMBL201279 0.82 PKM (0.46) TSHRSMN1; SMN2TDP1
SCHEMBL4398448 0.82 L3MBTL1 (0.40) MAPK1TSHRNPC1USP2RAB9A
SCHEMBL201929 0.81 MEN1 (0.44) TSHRALDH1A1LMNAHTTTNKS2
SCHEMBL202058 0.81 KDM4E (0.49) MAPK1TSHRRAB9ASMN1; SMN2ALDH1A1
SCHEMBL201109 0.81 FFAR1 (0.51) PARP10SMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 MAPK1 419/4885TSHR 1283/4885PARP10 3006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.