SCHEMBL31694750

SCHEMBL31694750

CC1Cn2c(nc3c(NC(=O)c4ccc(NS(=O)(=O)CCO)cc4N4CCC5(CC4)CC5)cccc32)C(C)O1

nearest known ligand 0.62

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31694738 0.88 KIF18A (0.61) KIF18A
SCHEMBL31613819 0.88 KIF18A (0.60) KIF18A
SCHEMBL31694764 0.86 KIF18A (0.63) KIF18A
SCHEMBL30842194 0.86 KIF18A (0.59) KIF18A
SCHEMBL31613838 0.84 KIF18A (0.59) KIF18A
SCHEMBL31613820 0.84 KIF18A (0.60) KIF18A
SCHEMBL31613841 0.83 KIF18A (0.62) KIF18A
SCHEMBL31694776 0.83 KIF18A (0.62) KIF18A
SCHEMBL31613828 0.83 KIF18A (0.61) KIF18A
SCHEMBL30842163 0.82 KIF18A (0.63) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070887-A1 AMIDE OR UREA COMPOUND SHENZHEN ZHONGGE BIOLOGICAL TECH CO LTD (CN) 2026-03-12 — — US disclosed
EP-4628486-A1 AMIDE OR UREA COMPOUND Shenzhen Zhongge Biological Technology Co., Ltd. (CN) 2025-10-08 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070887-A1 AMIDE OR UREA COMPOUND KIF18A, KIF18B, KIF23 KIF18A 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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