SCHEMBL31614449

SCHEMBL31614449

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 9/20 0.53
▸ OPRM1 P35372 8/20 0.53
▸ OPRK1 P41145 3/20 0.53
▸ TFPI P10646 1/20 0.52
▸ NPY5R Q15761 3/20 0.52
▸ NPY1R P25929 2/20 0.52
▸ NPY4R P50391 2/20 0.52
▸ BACE1 P56817 2/20 0.52
▸ BACE2 Q9Y5Z0 2/20 0.52
▸ APC P25054 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31614444 0.98 OPRD1 (0.56) OPRD1OPRM1OPRK1TFPINPY5R
SCHEMBL31614415 0.98 OPRD1 (0.55) OPRD1OPRM1OPRK1TFPINPY5R
SCHEMBL31614432 0.94 OPRD1 (0.56) OPRD1OPRM1OPRK1NPY5RNPY1R
SCHEMBL29375967 0.92 TFPI (0.59) OPRD1OPRM1OPRK1TFPINPY1R
SCHEMBL31614425 0.92 OPRD1 (0.56) OPRD1OPRM1OPRK1NPY1RNPY4R
SCHEMBL30721576 0.91 TFPI (0.61) OPRD1OPRM1OPRK1TFPI
SCHEMBL30612509 0.90 OPRM1 (0.59) OPRD1OPRM1OPRK1TFPIBACE1
SCHEMBL29525489 0.89 TFPI (0.63) OPRD1OPRM1OPRK1TFPI
SCHEMBL31614421 0.87 OPRD1 (0.57) OPRD1OPRM1OPRK1NPY1RNPY4R
SCHEMBL30473779 0.87 NPY4R (0.60) NPY5RNPY1RNPY4RBACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG OPRD1 4401/4885OPRM1 4237/4885OPRK1 3849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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