Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10580487 | 1.00 | ACHE (0.55) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28522595 | 0.87 | ACHE (0.56) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9054051 | 0.86 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9054056 | 0.86 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7786502 | 0.84 | ACHE (0.53) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28614954 | 0.84 | ACHE (0.58) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2486968 | 0.82 | NPC1 (0.55) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21359259 | 0.82 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7564677 | 0.82 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9682338 | 0.82 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122859-A1 | INDAZOLE-BASED MACROCYCLIC COMPOUNDS | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2025-06-12 | — | — | WO | disclosed |