Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28176264 | 0.98 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28522595 | 0.85 | ACHE (0.56) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10580487 | 0.84 | ACHE (0.55) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL31614616 | 0.84 | ACHE (0.55) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3806850 | 0.83 | ACHE (0.50) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21359173 | 0.83 | ACHE (0.50) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL10476088 | 0.83 | ACHE (0.50) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7064841 | 0.83 | ACHE (0.50) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL28614954 | 0.82 | ACHE (0.58) | ACHENPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL7564677 | 0.81 | ACHE (0.51) | ACHENPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157004-A1 | REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES | IDEC PHARMACEUTICALS CORPORATION (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000051976-A1 | REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES | IDEC PHARMACEUTICALS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |