SCHEMBL3162

SCHEMBL3162

Nc1nc2c(ncn2[C@H]2CC[C@@H](CO)O2)c(=O)[nH]1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.70
LMNA P02545 1/20 0.70
ALB P02768 1/20 0.70
MAPK1 P28482 1/20 0.70
CYP1A2 P05177 1/20 0.56
ADORA3 P0DMS8 1/20 0.52
POLB P06746 1/20 0.49
PNP P00491 1/20 0.48
HPGD P15428 1/20 0.48
TK1 P04183 1/20 0.47
HPRT1 P00492 1/20 0.47
STING1 Q86WV6 2/20 0.47
PDE3B Q13370 1/20 0.47
PDE3A Q14432 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8104283 1.00 ALDH1A1 (0.70) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL13833316 1.00 ALDH1A1 (0.70) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL19325461 1.00 ALDH1A1 (0.70) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL16695889 1.00 ALDH1A1 (0.70) ALDH1A1LMNAALBMAPK1CYP1A2
Phosphoric Acid SCHEMBL441920 0.96 ALDH1A1 (0.65) ALDH1A1LMNAALBMAPK1CYP1A2
Phosphoric Acid SCHEMBL7665465 0.96 ALDH1A1 (0.65) ALDH1A1LMNAALBMAPK1CYP1A2
Triphosphate SCHEMBL6066340 0.91 ALDH1A1 (0.59) ALDH1A1LMNAALBMAPK1CYP1A2
Zalcitabine SCHEMBL28057323 0.90 LMNA (0.58) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL24082233 0.89 ALDH1A1 (0.55) ALDH1A1LMNAALBMAPK1CYP1A2
SCHEMBL16552341 0.89 ALDH1A1 (0.55) ALDH1A1LMNAALBMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3495 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071254-A1 POLYMERASE MEDIATED END MODIFICATION OF ABSEQ BECTON DICKINSON CO (US) 2026-03-12 US claimed
EP-4612322-A1 POLYMERASE MEDIATED END MODIFICATION OF ABSEQ Becton, Dickinson and Company (US) 2025-09-10 EP claimed
US-20250263678-A1 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA REJUVENATION TECHNOLOGIES, INC. (US) 2025-08-21 US claimed
US-20250170228-A1 TERMINALLY MODIFIED RNA ARES CAPITAL CORPORATION, AS AGENT 2025-05-29 US claimed
CN-120019159-A Polymerase mediated ABSEQ terminal modification 贝克顿迪金森公司 2025-05-16 CN claimed
US-12173365-B2 Sequencing using non-natural nucleotides ULTIMA GENOMICS, INC. (US) 2024-12-24 US claimed
CN-119095964-A Multi-tail and multi-cap mRNA and uses thereof 博德研究所 2024-12-06 CN claimed
EP-4466074-A1 POLY-TAILED AND POLY-CAPPED MRNA AND USES THEREOF The Broad Institute Inc. (US) 2024-11-27 EP claimed
WO-2024192269-A2 ENZYMATIC METHODS AND COMPOSITIONS FOR POLYMERIZATION OF PHOSPHORAMIDATE AND THIOPHOSPHORAMIDATE-LINKED DNA THE GENERAL HOSPITAL CORPORATION (US) 2024-09-19 WO claimed
US-20240277872-A1 MODIFIED MRNA, MODIFIED NON-CODING RNA, AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2024-08-22 US claimed
WO-1989009055-A1 ANTIVIRAL COMPOSITION CONTAINING AROMATIC POLYCYCLIC DIONES AND NUCLEOSIDE ANALOGS AND METHOD FOR TREATING RETROVIRUS INFECTIONS NEW YORK UNIVERSITY (US) 1989-10-05 WO claimed
US-4861759-A Antiviral compositions and methods THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1989-08-29 US claimed
US-4835104-A Process for producing and purifying 2',3'-dideoxynucleosides, and process for producing 2',3'-dideoxy-2',3'-didehydronucleosides AJINOMOTO CO., INC., PATENT & LICENSING DEPARTMENT (JP) 1989-05-30 US claimed
EP-0312222-A1 Treatment of diseases caused by viruses Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1989-04-19 EP claimed
EP-0272007-A2 5- and 6- Succinimidyl - carboxylate isomers of rhodamine dyes APPLIED BIOSYSTEMS, INC. (US) 1988-06-22 EP claimed
EP-0270317-A2 Pharmaceutical compositions for the treatment of diseases caused by viruses Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1988-06-08 EP claimed
US-4704357-A TESTING DRUGS FOR EFFICARY AGAINST AIDS VIRUS UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1987-11-03 US claimed
EP-0216510-A2 Inhibition of in vitro infectivity and cytopathic effect of HTLV-III/LAV by 2'3'-dideoxyinosine, 2'3'-dideoxyguanosine, or 2'3'-dideoxyadenosine THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1987-04-01 EP claimed
WO-1987001284-A1 INHIBITION OF IN VITRO INFECTIVITY AND CYTOPATHIC EFFECT OF HTLV-III/LAV BY 2',3'-DIDEOXYNOSINE, 2',3'-DIDEOXYGUANOSINE, OR 2',3'-DIDEOXYADENOSINE UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) 1987-03-12 WO claimed
EP-0206497-A2 Therapeutic nucleosides and their preparation THE WELLCOME FOUNDATION LIMITED (GB) 1986-12-30 EP claimed