SCHEMBL31620050

SCHEMBL31620050

N=C(N)NCCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)NCCC(=O)N[C@H](CS)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 2/20 0.46
▸ APLNR P35414 1/20 0.46
▸ C5AR1 P21730 2/20 0.44
▸ NPY4R P50391 8/20 0.41
▸ NPY1R P25929 5/20 0.41
▸ NPY2R P49146 5/20 0.41
▸ NPY5R Q15761 5/20 0.41
▸ FOLH1 Q04609 1/20 0.41
▸ FNTA P49354 3/20 0.41
▸ FNTB P49356 3/20 0.41
▸ PGGT1B P53609 3/20 0.41
▸ GLP1R P43220 1/20 0.40
▸ SCTR P47872 1/20 0.40
▸ NMUR2 Q9GZQ4 1/20 0.40
▸ NMUR1 Q9HB89 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30787014 0.93 NPY4R (0.45) CTSLAPLNRC5AR1NPY4RNPY1R
SCHEMBL29511121 0.90 NPY4R (0.46) CTSLAPLNRNPY4RNPY1RNPY2R
SCHEMBL30045207 0.90 FNTA (0.47) APLNRNPY4RNPY1RNPY2RNPY5R
SCHEMBL31620054 0.88 FOLH1 (0.45) APLNRC5AR1FOLH1GLP1RSCTR
SCHEMBL30725662 0.87 APLNR (0.45) APLNRC5AR1NPY4RNPY1RNPY2R
SCHEMBL30264630 0.87 FNTA (0.46) APLNRC5AR1NPY4RNPY1RNPY2R
SCHEMBL29511195 0.87 FNTA (0.51) APLNRNPY4RNPY1RNPY2RNPY5R
SCHEMBL29482503 0.87 FNTA (0.51) APLNRNPY4RNPY1RNPY2RNPY5R
SCHEMBL29511116 0.85 FNTA (0.47) APLNRC5AR1NPY4RNPY1RNPY2R
SCHEMBL30044979 0.85 NPY4R (0.42) APLNRNPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120152725-A Methods of treating obesity using MC4R agonists 节奏制药公司 2025-06-13 — — CN disclosed
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