SCHEMBL29511121

SCHEMBL29511121

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 11/20 0.46
▸ NPY1R P25929 6/20 0.46
▸ NPY2R P49146 4/20 0.46
▸ NPY5R Q15761 4/20 0.46
▸ FNTA P49354 5/20 0.46
▸ FNTB P49356 5/20 0.46
▸ PGGT1B P53609 5/20 0.46
▸ APLNR P35414 1/20 0.42
▸ CTSL P07711 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30787014 0.98 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL30045207 0.95 FNTA (0.47) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29482503 0.95 FNTA (0.51) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29511195 0.95 FNTA (0.51) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29511116 0.92 FNTA (0.47) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL30725662 0.91 APLNR (0.45) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL31620050 0.90 CTSL (0.46) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29476479 0.90 FNTA (0.49) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL31252942 0.90 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RFNTA
SCHEMBL29461968 0.90 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5RFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS INC (US) 2026-01-01 — — US claimed
EP-4554607-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-05-21 — — EP claimed
WO-2024015880-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-01-18 — — WO claimed
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2026-03-26 — — US disclosed
EP-4554607-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST Rhythm Pharmaceuticals, Inc. (US) 2025-05-21 — — EP disclosed
WO-2024015880-A2 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST RHYTHM PHARMACEUTICALS, INC. (US) 2024-01-18 — — WO disclosed
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS IPSEN PHARMA SAS (FR) 2022-04-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001915-A1 METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST MC4R, NPY4R, MC3R NPY4R 2/4885NPY1R 8/4885NPY2R 7/4885
US-20260085092-A1 MELANOCORTIN RECEPTOR LIGANDS THRB, MC1R, MC5R NPY4R 41/4885NPY1R 9/4885NPY2R 12/4885
US-20220127305-A1 MELANOCORTIN RECEPTOR LIGANDS MC3R, MC1R, MC5R NPY4R 25/4885NPY1R 12/4885NPY2R 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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