Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.78 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | FLT3 | P36888 | 1/20 | 0.65 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 4/20 | 0.63 |
| ▸ | BRAF | P15056 | 4/20 | 0.63 |
| ▸ | KIT | P10721 | 3/20 | 0.63 |
| ▸ | RET | P07949 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620840 | 0.85 | KIT (0.76) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| SCHEMBL18762337 | 0.81 | KIT (0.75) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| SCHEMBL13765893 | 0.81 | ABL1 (0.87) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| SCHEMBL28021485 | 0.80 | KIT (0.72) | ABL1FGFR1EGFRBRAFKIT | |
| SCHEMBL29758813 | 0.80 | ABL1 (0.78) | ABL1FGFR1PDGFRAFLT3LRRK2 | |
| Olverembatinib SCHEMBL29387193 | 0.79 | ABL1 (1.00) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| Olverembatinib SCHEMBL3424528 | 0.79 | ABL1 (1.00) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| Olverembatinib SCHEMBL29514988 | 0.79 | ABL1 (1.00) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| Olverembatinib SCHEMBL14953130 | 0.78 | ABL1 (0.99) | ABL1FGFR1CYP2C9PDGFRACYP2C19 | |
| Olverembatinib SCHEMBL30456095 | 0.78 | ABL1 (0.99) | ABL1FGFR1CYP2C9PDGFRACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | disclosed |