Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 9/20 | 0.58 |
| ▸ | BRAF | P15056 | 8/20 | 0.56 |
| ▸ | EGFR | P00533 | 7/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | ABL2 | P42684 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620784 | 0.87 | BRAF (0.73) | KITBRAFEGFRCSF1R | |
| SCHEMBL31620840 | 0.82 | KIT (0.76) | KITABL1ABL2RET | |
| SCHEMBL5900585 | 0.81 | ABL1 (0.57) | KITBRAFEGFRABL1CSF1R | |
| SCHEMBL31620739 | 0.78 | BRAF (0.86) | KITBRAFEGFRCSF1R | |
| SCHEMBL27082370 | 0.76 | KIT (0.63) | KITBRAFEGFRABL1RET | |
| SCHEMBL28021485 | 0.76 | KIT (0.72) | KITBRAFEGFRABL1CSF1R | |
| SCHEMBL5900504 | 0.75 | EGFR (0.63) | KITBRAFEGFRABL1CSF1R | |
| SCHEMBL31620732 | 0.75 | KIT (0.59) | KITBRAFEGFRABL1RET | |
| SCHEMBL14318406 | 0.75 | KIT (0.77) | KITBRAFEGFRABL1CSF1R | |
| SCHEMBL29562197 | 0.75 | KIT (0.77) | KITBRAFEGFRABL1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136781-A | ROR 1-targeted inhibitor and synthesis method and application thereof | 北京大学 | 2025-06-13 | — | — | CN | disclosed |