Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31620888 | 1.00 | GPR183 (0.53) | GPR183LMNANPC1MAPTHDAC1 | |
| SCHEMBL31620871 | 0.90 | ALDH1A1 (0.52) | GPR183LMNANPC1MAPTALDH1A1 | |
| SCHEMBL31620933 | 0.90 | ALDH1A1 (0.52) | GPR183LMNANPC1MAPTALDH1A1 | |
| SCHEMBL31620940 | 0.88 | P4HB (0.48) | LMNAMAPTHDAC1HDAC6ALDH1A1 | |
| SCHEMBL31620924 | 0.87 | TRPV1 (0.49) | LMNAMAPTHDAC1HDAC6ALDH1A1 | |
| SCHEMBL31620910 | 0.87 | ALDH1A1 (0.50) | LMNANPC1MAPTHDAC1HDAC6 | |
| SCHEMBL31620900 | 0.84 | GPR183 (0.46) | GPR183LMNANPC1ALDH1A1GAA | |
| SCHEMBL31620866 | 0.82 | ALDH1A1 (0.44) | GPR183LMNANPC1MAPTALDH1A1 | |
| SCHEMBL31620932 | 0.82 | ALDH1A1 (0.51) | LMNAMAPTALDH1A1GAAHPGD | |
| SCHEMBL31620905 | 0.81 | HDAC1 (0.53) | NPC1MAPTHDAC1HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136796-A | Alpha, beta unsaturated ketone derivative and preparation method and application thereof | 河南大学 | 2025-06-13 | — | — | CN | disclosed |