SCHEMBL316249

SCHEMBL316249

CC=CC(=CC)C=C(C)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 1/20 0.40
KDM1A O60341 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
NR4A1 P22736 1/20 0.33
NR4A2 P43354 1/20 0.33
NR4A3 Q92570 1/20 0.33
RECQL P46063 1/20 0.32
ATM Q13315 1/20 0.32
NFE2L2 Q16236 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1638383 0.80 AKT1 (0.42) DEGS1KDM1ASMN1; SMN2MEN1KMT2A
SCHEMBL564797 0.74 ALDH1A1 (0.40) DEGS1KDM1AKMT2ALMNARECQL
SCHEMBL18570750 0.74 DEGS1 (0.44) DEGS1KDM1ASMN1; SMN2MEN1KMT2A
SCHEMBL513852 0.73 KDM1A (0.48) DEGS1KDM1AMEN1KMT2ALMNA
SCHEMBL475092 0.73 KDM1A (0.48) DEGS1KDM1AMEN1KMT2ALMNA
SCHEMBL395021 0.73 KDM1A (0.48) DEGS1KDM1AMEN1KMT2ALMNA
SCHEMBL23395187 0.72 DEGS1 (0.43) DEGS1KDM1ASMN1; SMN2MEN1KMT2A
SCHEMBL19052237 0.72 KDM1A (0.38) DEGS1KDM1ASMN1; SMN2LMNACES2
SCHEMBL22572689 0.71 RECQL (0.52) SMN1; SMN2MEN1KMT2ALMNAHPGD
SCHEMBL1536443 0.70 NR4A2 (0.60) DEGS1KDM1ASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934285-A1 IMPACT MODIFIED POLY(ARYLENE ETHER)/POLYESTER BLENDS AND METHOD FOR PREPARING THEM General Electric Company (US) 2008-06-25 EP claimed
WO-2007027387-A1 IMPACT MODIFIED POLY(ARYLENE ETHER)/POLYESTER BLENDS AND METHOD FOR PREPARING THEM GENERAL ELECTRIC COMPANY (US) 2007-03-08 WO claimed
US-20070049690-A1 Impact modified poly(arylene ether)/polyester blends and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-01 US claimed
US-10166441-B2 Three-cover-layer golf ball having transparent or plasticized polyamide intermediate layer ACUSHNET COMPANY (US) 2019-01-01 US disclosed
US-20170266507-A1 THREE-COVER-LAYER GOLF BALL HAVING TRANSPARENT OR PLASTICIZED POLYAMIDE INTERMEDIATE LAYER ACUSHNET COMPANY (US) 2017-09-21 US disclosed
US-9669265-B2 Three-cover-layer golf ball having transparent or plasticized polyamide intermediate layer ACUSHNET COMPANY (US) 2017-06-06 US disclosed
US-9566474-B2 Golf ball with soft coating and hard cover NIKE, INC. (US) 2017-02-14 US disclosed
US-20160256749-A1 Three-Cover-Layer Golf Ball Comprising Intermediate Layer Including A Plasticized Polyester Composition ACUSHNET COMPANY (US) 2016-09-08 US disclosed
US-9339696-B2 Three-cover-layer golf ball comprising intermediate layer including a plasticized polyester composition ACUSHNET COMPANY (US) 2016-05-17 US disclosed
US-20150111669-A1 Three-Cover-Layer Golf Ball Comprising Intermediate Layer Including A Plasticized Polyester Composition ACUSHNET COMPANY (US) 2015-04-23 US disclosed
US-20150005107-A1 THREE-COVER-LAYER GOLF BALL HAVING TRANSPARENT OR PLASTICIZED POLYAMIDE INTERMEDIATE LAYER ACUSHNET COMPANY (US) 2015-01-01 US disclosed
WO-2009076133-A2 THERMOPLASTIC POLY(ARYLENE ETHER)/POLYAMIDE BLENDS AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-18 WO disclosed
US-20090146109-A1 THERMOPLASTIC POLY(ARYLENE ETHER)/POLYAMIDE BLENDS AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP BV (NL) 2009-06-11 US disclosed
US-20090036606-A1 THERMOPLASTIC POLY(ARYLENE ETHER) / POLYESTER BLENDS AND METHOD OF MAKING GENERAL ELECTRIC COMPANY (US) 2009-02-05 US disclosed
US-20090014692-A1 THERMOPLASTIC POLY(ARYLENE ETHER) / POLYESTER BLENDS AND ARTICLES THEREOF GENERAL ELECTRIC COMPANY (US) 2009-01-15 US disclosed
WO-2009009729-A1 THERMOPLASTIC POLY (ARYLENE ETHER)/POLYESTER BLENDS AND METHOD OF MAKING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-01-15 WO disclosed
WO-2009009731-A2 THERMOPLASTIC POLY(ARYLENE ETHER)/POLYESTER BLENDS AND ARTICLES THEREOF SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-01-15 WO disclosed
EP-1934285-A1 IMPACT MODIFIED POLY(ARYLENE ETHER)/POLYESTER BLENDS AND METHOD FOR PREPARING THEM General Electric Company (US) 2008-06-25 EP disclosed
WO-2007027387-A1 IMPACT MODIFIED POLY(ARYLENE ETHER)/POLYESTER BLENDS AND METHOD FOR PREPARING THEM GENERAL ELECTRIC COMPANY (US) 2007-03-08 WO disclosed
US-20070049690-A1 Impact modified poly(arylene ether)/polyester blends and method CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-01 US disclosed