Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 4/20 | 0.33 |
| ▸ | BRAF | P15056 | 4/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KIF5B | P33176 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637189 | 0.81 | IDO1 (0.38) | IDO1AXLMETAP2TRPA1 | |
| SCHEMBL21542750 | 0.80 | IDO1 (0.37) | IDO1AXLMETAP2TRPA1 | |
| SCHEMBL27188140 | 0.78 | BRD4 (0.39) | BRD4IDO1AXLMETAP2KDM4E | |
| SCHEMBL29712207 | 0.78 | BRD4 (0.39) | BRD4IDO1AXLMETAP2KDM4E | |
| SCHEMBL24373309 | 0.78 | ESR2 (0.37) | IDO1MAP4K1TRPA1 | |
| SCHEMBL14663113 | 0.78 | TRPA1 (0.37) | IDO1AXLMETAP2TRPA1 | |
| SCHEMBL29478864 | 0.78 | ESR2 (0.37) | IDO1MAP4K1TRPA1 | |
| SCHEMBL18552652 | 0.77 | MTNR1A (0.39) | BRD4RET | |
| SCHEMBL28782096 | 0.77 | AXL (0.50) | IDO1AXLMETAP2CYP1A2TRPA1 | |
| SCHEMBL20315160 | 0.76 | IDO1 (0.37) | IDO1AXLMAP4K1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129135-A2 | COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-06-19 | — | — | WO | disclosed |