Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683792 | 0.89 | GAA (0.60) | GAABCL9CTNNB1HTR2AELANE | |
| SCHEMBL4876569 | 0.88 | GAA (0.53) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL4876562 | 0.88 | GAA (0.53) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL16261887 | 0.84 | HTR2A (0.59) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL515913 | 0.83 | GAA (0.57) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL9435291 | 0.83 | GAA (0.57) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL2235530 | 0.82 | HTR2A (0.54) | GAABCL9CTNNB1HTR2AELANE | |
| Water SCHEMBL4754930 | 0.81 | GAA (0.55) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL4752026 | 0.81 | GAA (0.58) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL14307582 | 0.81 | GAA (0.58) | GAABCL9CTNNB1HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025129116-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2025-06-19 | — | — | WO | disclosed |