Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4876569 | 1.00 | GAA (0.53) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL31627733 | 0.88 | GAA (0.53) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL16261887 | 0.84 | HTR2A (0.59) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL4683792 | 0.82 | GAA (0.60) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL4752026 | 0.81 | GAA (0.58) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL14307582 | 0.81 | GAA (0.58) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL2233659 | 0.81 | HTR2A (0.52) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| SCHEMBL9365950 | 0.81 | HTR2A (0.55) | GAABCL9CTNNB1HTR2AALDH1A1 | |
| 4-Nitrophenyl Acetate SCHEMBL74985 | 0.80 | GAA (0.66) | GAABCL9CTNNB1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18285287 | 0.80 | GAA (0.57) | GAABCL9CTNNB1HTR2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242644-A1 | Factor Viia Inhibitor | PHARMACYCLICS, INC. (US) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242644-A1 | Factor Viia Inhibitor | F7, F9, F5 | GAA 1680/4885BCL9 297/4885CTNNB1 4072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.