Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375556 | 1.00 | NAAA (0.40) | NAAASMN1; SMN2NPC1RAB9APREP | |
| SCHEMBL31375607 | 0.86 | NAAA (0.46) | NAAASMN1; SMN2PREPIDO1TDO2 | |
| SCHEMBL31628107 | 0.86 | LMNA (0.49) | NAAANPC1RAB9APREPIDO1 | |
| SCHEMBL29796820 | 0.86 | HDAC1 (0.39) | SMN1; SMN2NPC1RAB9AHPGDHDAC1 | |
| SCHEMBL26962726 | 0.86 | HDAC1 (0.39) | SMN1; SMN2NPC1RAB9AHPGDHDAC1 | |
| SCHEMBL26961985 | 0.86 | HDAC1 (0.42) | SMN1; SMN2NPC1RAB9AHPGDTDP1 | |
| SCHEMBL10672051 | 0.81 | NAAA (0.44) | NAAASMN1; SMN2PREPIDO1TDO2 | |
| SCHEMBL3485068 | 0.81 | NAAA (0.51) | NAAAPREPIDO1TDO2 | |
| SCHEMBL3484480 | 0.81 | NAAA (0.51) | NAAAPREPIDO1TDO2 | |
| SCHEMBL3484484 | 0.81 | NAAA (0.51) | NAAAPREPIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568959-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |