Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629209 | 0.92 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL31629482 | 0.87 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL31629090 | 0.86 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL31629402 | 0.85 | SLC6A2 (0.32) | PTGS2 | |
| SCHEMBL31629652 | 0.82 | PTGS2 (0.32) | PTGS2 | |
| SCHEMBL31629587 | 0.81 | S1PR1 (0.31) | — | |
| SCHEMBL31631865 | 0.79 | F2RL1 (0.35) | PTGS2 | |
| SCHEMBL31629223 | 0.77 | TRPV1 (0.37) | — | |
| SCHEMBL31629065 | 0.76 | SLC6A2 (0.31) | — | |
| SCHEMBL31629592 | 0.76 | TRAP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125666-A1 | SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |