⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629052 | 0.91 | — | — | |
| SCHEMBL31629330 | 0.88 | — | — | |
| SCHEMBL31629164 | 0.87 | — | — | |
| SCHEMBL31629065 | 0.84 | SLC6A2 (0.31) | — | |
| SCHEMBL31629264 | 0.83 | F2RL1 (0.31) | — | |
| SCHEMBL31629117 | 0.81 | SLC6A2 (0.30) | — | |
| SCHEMBL31629652 | 0.80 | PTGS2 (0.32) | — | |
| SCHEMBL31629326 | 0.80 | GABRP (0.31) | — | |
| SCHEMBL31628951 | 0.79 | MAPK1 (0.33) | — | |
| SCHEMBL31629090 | 0.79 | PTGS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025125666-A1 | SUBSTITUTED IMIDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-06-19 | — | — | WO | disclosed |