SCHEMBL31633617

SCHEMBL31633617

Cc1cnc(C)c(C(=O)O)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
KMT2A Q03164 1/20 0.50
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NOTUM Q6P988 1/20 0.39
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38
GABRG1 Q8N1C3 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978399 1.00 KDM4E (0.50) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL28331329 0.84 KDM4E (0.48) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL28849171 0.81 KDM4E (0.70) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL2807021 0.78 KDM4E (0.56) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL21825916 0.74 LDHA (0.40) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL52408 0.74 KDM4E (0.61) KDM4EKMT2AALDH1A1SMN1; SMN2NOTUM
SCHEMBL1769880 0.74 KDM4E (0.39) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL21826098 0.74 KDM4E (0.43) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL4239168 0.73 HCAR2 (0.46) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL410293 0.73 KMT2A (0.45) KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192327-A Preparation method of pyridine dicarboxylic anhydride solution 张家港市国泰华荣化工新材料有限公司 2025-06-24 CN disclosed