Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747657 | 0.83 | CYP3A4 (0.39) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7788149 | 0.83 | GABRP (0.38) | KDM4EKMT2AALDH1A1LDHAGABRP | |
| SCHEMBL28331329 | 0.81 | KDM4E (0.48) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21825916 | 0.79 | LDHA (0.40) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7666078 | 0.79 | LDHA (0.36) | KDM4EKMT2AALDH1A1MAPK1LDHA | |
| SCHEMBL28180665 | 0.79 | AGXT (0.45) | KDM4EKMT2AALDH1A1MAPK1GABRP | |
| SCHEMBL16445970 | 0.78 | KDM4E (0.46) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7672020 | 0.78 | HCAR2 (0.41) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL21826454 | 0.75 | KDM4E (0.38) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL978399 | 0.74 | KDM4E (0.50) | KDM4EKMT2AALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352629-B1 | Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss | OREAL (FR) | 2011-06-22 | — | — | EP | claimed |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL | 2009-08-27 | — | — | US | claimed |
| US-9266902-B2 | Labelling reagents having a pyridine nucleus bearing a diazomethyl function, process for synthesis of such reagents and processes for detection of biological molecules | BIOMERIEUX (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2011-05-12 | — | — | US | disclosed |
| US-20100105741-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL (FR) | 2010-04-29 | — | — | US | disclosed |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | L'OREAL | 2009-08-27 | — | — | US | disclosed |
| US-20080293696-A1 | 2-Aminoarylcarboxamides Useful as Cancer Chemotherapeutic Agents | BAYER PHARMACEUTICALS CORPORATION (US) | 2008-11-27 | — | — | US | disclosed |
| EP-0069033-B1 | HERBICIDAL AMIDE AND ESTER DERIVATIVES OF PYRIDINE, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION | RHONE-POULENC AGROCHIMIE (FR) | 1985-09-04 | — | — | EP | disclosed |
| EP-0069033-A1 | Herbicidal amide and ester derivatives of pyridine, process for their preparation and their application | RHONE-POULENC AGROCHIMIE (FR) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110111514-A1 | LABELLING REAGENTS HAVING A PYRIDINE NUCLEUS BEARING A DIAZOMETHYL FUNCTION, PROCESS FOR SYNTHESIS OF SUCH REAGENTS AND PROCESSES FOR DETECTION OF BIOLOGICAL MOLECULES | DUT, NCL, POLRMT | KDM4E 1099/4885KMT2A 300/4885ALDH1A1 2683/4885 |
| US-20080293696-A1 | 2-Aminoarylcarboxamides Useful as Cancer Chemotherapeutic Agents | ABCC3, HCCS, ABCC2 | KDM4E 975/4885KMT2A 519/4885ALDH1A1 611/4885 |
| US-20100105741-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | AKR1C3, MC1R, KRT18 | KDM4E 1459/4885KMT2A 2563/4885ALDH1A1 1657/4885 |
| US-20090215837-A1 | ADMINISTRATION OF PYRIDINEDICARBOXYLIC ACID COMPOUNDS FOR STIMULATING OR INDUCING THE GROWTH OF HUMAN KERATINOUS FIBERS AND/OR ARRESTING THEIR LOSS | AKR1C3, MC1R, KRT18 | KDM4E 1459/4885KMT2A 2563/4885ALDH1A1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.