SCHEMBL31633626

SCHEMBL31633626

OC1CC2(CNC2Cc2ccccc2)C1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 2/20 0.38
HDAC8 Q9BY41 2/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34463931 0.79 POLB (0.42) GBA1HDAC8POLB
SCHEMBL16616098 0.77 GBA1 (0.47) GBA1HDAC8POLB
SCHEMBL30428263 0.73 HDAC8 (0.35) GBA1HDAC8POLB
SCHEMBL31006193 0.65 GBA1 (0.34) GBA1HDAC8POLB
SCHEMBL28555751 0.65 MAOA (0.44)
SCHEMBL30428125 0.65 POLB (0.41) GBA1HDAC8POLB
SCHEMBL17959206 0.64 POLB (0.44) GBA1HDAC8POLB
SCHEMBL19452159 0.64 ACE (0.36) GBA1HDAC8POLB
SCHEMBL23477892 0.63 POLB (0.40) GBA1HDAC8POLB
SCHEMBL27290836 0.63 POLB (0.44) POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192257-A Preparation method of 6-hydroxy-2-azaspiro [3.3] heptane compound and intermediate thereof 浙江中科创越药业有限公司 2025-06-24 CN disclosed