Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24752653 | 0.90 | BAZ2B (0.37) | PARP1LMNAMAPTHTR4 | |
| SCHEMBL11957589 | 0.79 | KDM4E (0.44) | PARP1LMNAMAPTHTR4KDM4E | |
| SCHEMBL29644689 | 0.78 | KDM4E (0.48) | PARP1LMNAMAPTHTR4KDM4E | |
| SCHEMBL10320877 | 0.78 | KDM4E (0.48) | PARP1LMNAMAPTHTR4KDM4E | |
| SCHEMBL4882971 | 0.77 | KDM4E (0.41) | PARP1LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL18181800 | 0.77 | PARP1 (0.51) | PARP1LMNAMAPTHTR4KDM4E | |
| SCHEMBL31634117 | 0.76 | — | — | |
| SCHEMBL31634068 | 0.74 | MTNR1B (0.41) | — | |
| SCHEMBL11956872 | 0.74 | HTR4 (0.48) | HTR4HTR1AADRA2CACHEPTGS1 | |
| SCHEMBL14995541 | 0.73 | BAZ2B (0.43) | PARP1LMNAMAPTHTR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192307-A | Compounds targeting p53 mutations | 上海齐鲁制药研究中心有限公司 | 2025-06-24 | — | — | CN | disclosed |