Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCND1 | P24385 | 18/20 | 0.49 |
| ▸ | CDK2 | P24941 | 15/20 | 0.49 |
| ▸ | CDK4 | P11802 | 12/20 | 0.49 |
| ▸ | CCND2 | P30279 | 9/20 | 0.49 |
| ▸ | CCND3 | P30281 | 9/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 9/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | CDK9 | P50750 | 3/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828611 | 1.00 | CCND1 (0.49) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL574660 | 0.94 | CCND1 (0.56) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL29990953 | 0.94 | CCND1 (0.56) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL4828470 | 0.93 | CCND1 (0.57) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL29507717 | 0.88 | CCND1 (0.42) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL22860605 | 0.85 | CCND1 (0.40) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL31153373 | 0.84 | CDK2 (0.58) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL19857375 | 0.84 | CDK2 (0.58) | CCND1CDK2CDK4CCND2CCND3 | |
| SCHEMBL4713281 | 0.82 | L3MBTL1 (0.47) | CCND1CDK2CCNE1CDK6 | |
| SCHEMBL24669667 | 0.82 | CDK2 (0.53) | CCND1CDK2CDK4CCND2CCND3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137393-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASES 2, 4, AND 6 VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |